Fungal mutants not solved by internal amplification controls.

I was interested to read Rodríguez et al. (2012) on PCR to detect verrucosin producing fungi in food and cultures. However, their interpretation regarding mutated strains and internal amplification controls (IAC) appears to be incorrect, although they referred to our papers on the issue. It is worth restating to the wider scientific community that fungi may be mutated by self produced mutagens and enzyme inhibitors leading to false negative or positive results (Paterson et al., 2008; Paterson and Lima 2009) for which an IAC is irrelevant. Finally, interpretations of PCR results from cultures or food require to consider these possibilities. I look forward to your reply.